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David, I appreciate your research into the success stats for the pallidotomy procedure, and the weighty decision you and your wife confront. I must confess though that the thing that caught my eye in your response to the letter from the neurologist was the statement that the new doctors had almost eliminated the dyskenesia and on/off for Aviva. As a young onset patient with lots of dyskenesia and on/off, I can't resist asking what the magic combination is?!?! The most even times I have had have been on a combination of Eldypryl, Sinemet, and Ropinerole (a study drug not yet available for use), but my honeymoon is over and Smith Kline is no longer interested in my reactions to Ropinerole. Can you give us a breakdown of what is working? With much hope for the future....Kathie Tollifson