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I am wondering if there is any connection between the subject enzyme mentioned in Hans van Zyl's message and the tyrosinase enzyme central to the Wilson's disease. The latter was from the Grolier encyclopedia article on copper. The question that Dr. Jeffrey Tosk mentioned at one time about the black pigmentation of the substantia nigra being odd in the center of the brain where there is no light occurred to him. I am curious about this, too. The mention in the copper article that albino animals having a lack perhaps of the copper-containing tyrosinase prompts the question <does the albino brain substantia nigra exist?> Is it black? The conjecture by Dr. Tosk that there is no light in the brain is probably not true. There is some transmissibility to some of the electromagnetic spectrum. This energy would tend to be absorbed by the black matter and raise it's temperature. Could this be a clue worth pursuing? Does anyone have more complete detail about Wilson's disease? Perhaps Jeffrey Romanyshyn will be enlightened by the doctor he plans to consult about the disease some have declared him to have. The pathology postmortem description of the substantia nigra of persons afflicted with Wilson's as to pigmentation and Lewy bodies, et cetera might be clues. If excess iron is PD marking, does Wilson's have excess copper? Enough for now. Ron <[log in to unmask]> Ronald F. Vetter