I wish to stay clear of generalizations regarding "generics" and stick to sinemet and its generic . I've used both and can find no difference in their action. The generic I buy {at about half the Sinemet price} is made by TEVA, an excellent Israeli company. They make Sinemet for Merck and their manufacture goes two two tabletting devices. One produces pills in an ovoid shape {Sinemet} and the other in round form, . If you ask your pharmacist, he will tell you the name of the generic manufacturer and then you can check it out . SAM [log in to unmask]