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SINEMET FIZZ!!! THE FIZZ TAKE ONE 12OZ BOTTLE OF GINGER ALE. DROP 1 25/250 SINEMET OR 3 1/2 SINEMET 10/10 0 INTO GINGER ALE AFTER THE (PLOP PLOP FIZZ FIZZ) THE GINGER ALE WILL HAVE APPROXIMATELY 1MG PER ML OF SINEMET. IF YOU KEEP IT COOL IT WILL BE STABLE FOR 24 HOURS. MAKING IT EASY: MOST PEOPLE SWALLOW FROM 20ML TO 30ML. SO WE CAN SAFELY SAY THAT EVERY SWALLOW IS ABOUT 25MG OF SINEMET. THAT'S ABOUT 1/4 OF THE SMALLEST SINEMET MADE . HOW MUCH? SINEMET HAS A SHORT HALF LIFE . WHAT THIS MEANS IS THAT IN ABOUT 1 1/2 HOUR 1/2 OF A SINEMET DOSE IS GONE. SO TO HAVE IT LAST FOR 4 HOURS YOU NEED ABOUT TWICE AS MUCH AS FOR EVERY 2 HOURS. HOW TO USE THE FIZZ THE TWO MAIN WAYS TO USE THE SINEMET FIZZ ARE. 1. AS A RESCUE WHEN YOU HAVE OFF TIMES IN BETWEEN DOSES. TO DO THIS YOU SIMPLY CARRY A BOTTLE OF SINEMET FIZZ WITH YOU. WHEN YOU FEEL YOU ARE GOING OFF TAKE 1 SWALLOW EVERY 5 TO 10 MINUETS UNTIL YOU FEEL BETTER. 2. AS A STANDARD DOSE EVERY 1 TO 2 HOURS. THIS IS DONE BY TAKING TOTAL SINEMET DOSE PER DAY DIVIDED BY THE NUMBER OF HOURS YOU ARE UP. THIS WILL GIVE YOU THE DOSE YOU NEED EVERY HOUR. REMEMBERING SINEMETS SHORT HALF LIFE YOU ADJUST TH E DOSE. (IF YOU WANT TO TAKE IT EVERY 2 HOURS DOUBLE THE HOURLY DOSE ETC.) WHY IT WORKS? SINEMET IS NOT ABSORBED IN THE STOMACH IT HAS TO PASS INTO THE SMALL INTESTINE TO DO THIS IT HAS TO PASS THROUGH THE PYLORIC VALVE. THIS CAN BE A MASSIVE PROBLEM SENSE MOST PARKINSONIANS HAVE INTESTINAL SLOWNESS. THIS CAN MEAN UP TO 3 HOURS OR MORE BEFORE THE PYLORIC VALVE OPENS. THE SINEMET FIZZ SOLVES THIS PROBLEM BECAUSE IT IS LIQUID IT GETS PAST THE PYLORIC VALVE EVEN IF ITS CLO SED. THE SUGAR HELPS IT GET ABSORBED TROUGH THE INTESTINAL WALL MUCH FASTER. SUGAR IS TAKEN UP BY THE BRAIN VERY QUICKLY AND TENDS TO TAKE THE S INEMET WITH IT. REMEMBER THIS IT NOT MEDICAL ADVICE TALK TO YOUR DOCTOR BEFORE YOU CHANGE ANY THING REGARDING YOUR HEALTH C ARE TONY SCHOONENBERG MOVEMENT DISORDERS TEAM PEAR REP/ COORDINATOR LOMA LINDA UNIVERSITY MEDICAL CENTER LOMA LINDA CA 92354 909-824-4952 office 909-824-4825 fax email: [log in to unmask]