I to want to thank Dr. Kelly for his responce to the N. y. times article the fallowing is a reprint of that responce again thanks. *--* 03-17-95 - 04:44:07 *--* 7 Message 7: From <@UBVM.CC.BUFFALO.EDU:[log in to unmask]> Thu Mar 16 18:19:00 1 995 Date: Thu, 16 Mar 1995 21:06:00 EST Reply-To: "Parkinson's Disease - Information Exchange Network" <[log in to unmask]> Sender: "Parkinson's Disease - Information Exchange Network" <[log in to unmask]> From: "P.J. Kelly" <[log in to unmask]> Subject: Re: New York Times Article 3/16/95 Comments: To: [log in to unmask] To: Multiple recipients of list PARKINSN <[log in to unmask] LO.EDU> To Listmembers: Friends: Ordinarily I would not get into a debate over inaccuracies published in a newspaper. After all, it happens all of the time. However, the coverage of Pallidotomy in the recent New York Times article (3/16/95) was so distorted and unfair that it is unconscionable that I feel that I should comment even --More--[Hit space to continue or q to stop.] though it may seem self-serving since I do Pallidotomies within a carefully --More--[Hit space to continue or q to stop.] controlled research effort at New York University Medical Center. Please be assured that I could stop doing pallidotomies tomarrow (they comprise less than 10 percent of my practice) and would have plenty of work-brain tumors, thalamotomies and other general neurosurgical procedures. I have no real vested interest in the procedure except that I feel that it's a good operation in selected patients with Parkinson's disease. However, this reporter has done a major disservice to the community of people suffering from Parkinson's disease in a vicious attempt to slander a member of the medical community who has done much more good than harm. In the process she has destroyed hope for many who wish for a better life but are now scared out of their wits of having a surgery which could help them. She has created needless anxiety in those who plan on having the operation. First, some of the points raised in the article are true but incomplete. All surgery (including pallidotomy) has risks. In addition a good result cannot be expected in each and every individual. This is true for any surgical procedure one can name. Dr. Iaconno has done over 500 pallidotomies and as in any surgical series a certain percentage of patients may be worse off (complications). It seems as if the New York Times has found a few of them-that's not surprising in a large series such as his. Had they wanted to do a marginally adequate job of reporting they would have found many more --More--[Hit space to continue or q to stop.] individuals who had benefitted from the procedure than had been hurt by it. There is no doubt about the fact that every patient who undergoes any medical procedure; surgery, getting intravenous contrast for a diagnostic test or even filling a prescription for medication assumes a risk. Obviously, the doctor and the patient hope for the desired benefit; but there is no way to predict if a patient will have an adverse effect (if there were, we wouldn't do it). All of us are human (even if some of us have an MD after our name) and none of would consciously do harm to another human being. Nonetheless, as a neurosurgeon, I freely admit that some of the people that I've operated upon are worse off after my procedures. If I had only known prior to surgery that this person or that would suffer a complication in my hands, I wouldn't have touched them. But every surgery has a benefit to risk ratio; with thalamotomy in Parkinson's disease there is a 90% chance that we'll stop tremor-a 4.8 percent chance that the patient will have some side effect or complication. With Pallidotomy-a very similar procedure- the benefit is harder to measure (tremor is either there or it isn't; pronouncement of improvement in rigidity and bradykinesia relies on the subjective impressions of the patient and examiner). Nevertheless, with pallidotomy the benefit appears to be about 80% and the risk of complications with a carefully done proceure about 5%. For example if Dr Iaconno performed 500 pallidotomies, there would be about 25 people who are worse off by some --More--[Hit space to continue or q to stop.] complication or other, but 400 people who derived benefit and now think he's a great guy - even though the New York Times in a feeble effort to sell newspapers finds it in their interest not to agree. What about the effects of the procedure not lasting? Some patients have had only short term benefit to pallidotomy. What the NYT article didn't say is that many of Laitinen's patients were found to have derived long term benefit. Please understand this. Parkinson's disease is a progressive disease whose course is unaltered by treatment. The best a physician can do is to create plateaus in the patient's disability by palliating the symptoms causing that disability. All initially effective therapy (L-DOPA, Sinamet, thalamotomy, pallidotomy) results in "temporary" improvement. But temporary can be months or many years until the disease catches up again. As I'm sure all of you know-Parkinson's disease progresses faster in some people than in others. Now with the above as background, I hope that the members of the list will indulge me as I take this silly "reporter" and her article apart: (My comments will be in CAPS, those following the >represent the original text of the article)