This is the forwarded comments from Dr. Lieberman to the New York Time, Letter to the Editor page. THE COMPLETE TEXT OF Dr. Lieberman's LETTER TO THE EDITOR FOLLOWS: March 20, 1995 Editors, New York Times New York, New York Dear Editors: The March 16, 1995 Times article on pallidotomy, a surgical treatment for Parkinson's disease, differed markedly from the recent Wall Street Journal article on the same procedure. The Journal article was positive, your article was negative. Why the discrepancy? The answer, not emphasized in either article, is patient selection and operative technique. Pallidotomy as a treatment for Parkinson's disease is fifty years old. The resurgence of interest is due to improved methods of locating. But even after it is located, pallidotomy is not tonsillectomy or herniorrhaphy. It cannot be done in any hospital by any surgeon. Patient selection is important. A surgeon quoted in your article couldn't distinguish Multiple Sclerosis from Parkinson's disease. If he couldn't distinguish the two he shouldn't have done the procedure. But what about the more difficult task of distinguishing between Parkinson's disease and the look-a-like disorders such as Progressive Supranuclear Palsy? Striatonigral Degeneration? Multi-System Atrophy? Such distinctions are necessary because the look-a-like disorders don't respond as well as Parkinson's disease to pallidotomy. The pallidum is located using high field Magnetic Resonance Imaging (MRI), a technique available almost anywhere in the United States. But locating the pallidum is not enough. The pallidum must be distinguished from the adjacent internal capsule. Failure to do so results in stroke. The pallidum must be distinguished from the adjacent optic tract. Failure to do so results in partial blindness. The internal pallidum must be distinguished from the external pallidum. Failure to do so results in increased, not decreased Parkinson symptoms. Finally the topography of the internal pallidum must be mapped and its volume determined. Failure to do so results in only partial relief of symptoms. The pallidum is distinguished from its surrounding structures, the internal is distinguished from the external pallidum and the topography of the internal pallidum is defined through single-cell, intra-operative recordings performed by a trained neurophysiologist. The difference between doing the procedure with monitoring and without is the difference between the results described in your article and the Journal's article. Truly, Abraham Lieberman, M.D. Chairman, Medical Advisory Board American Parkinson Disease Association Chief, Movement Disorders Barrow Neurological Institute Phoenix, Arizona, John Cottingham [log in to unmask]