Dear Bob, I do not know of any systematic studies that look at the effect of pallidotomy on speech. Now that the popularity of pallidotomy has increased so much, I am thinking of examining that issue myself. I'm sorry to hear that your mother's speech is worse. Speech therapy for Parkinson's disease has waxed and waned in popularity, like the pallidotomy! An article written by Martha Taylor Sarno in 1968 (in the _Archives of Physical Medicine and Rehabilitation_, vol. 49, pp. 269-275) set the stage of despair regarding speech therapy for many years. She states that over 300 patients were treated in her program over a 15 year period, and "it is our strong impression that the speech of these patients does not improve with treatment." However, new techniques and approaches are reporting encouraging results that last even after therapy has ended (see Ramig, Bonitati, Lemke, & Horii, 1994, "Voice treatment for patients with Parkinson disease: Development of an approach and preliminary efficacy data" in _Journal of Medical Speech-Language Pathology_, vol. 2, no. 3, pp. 191-209.). In the case of a patient who has had brain surgery (pallidotomy or otherwise), the findings of these studies may not apply. I would strongly encourage your mother to have a thorough speech evaluation conducted by a speech-language pathologist. It may be possible to improve her speech, but even if it is not, the speech-language pathologist can help your mother develop alternate methods of communication. This is so important for her quality of life. Good luck. Nancy Pearl Solomon, Ph.D. Asst. Research Scientist Dept. of Speech Pathology and Audiology, and National Center for Voice and Speech University of Iowa