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I was interested in your message re Klonopin to John Cottingham. I have read his interesting messages often but have not seen messages from you. I too suffer with RLS and PD and treat with 1/2 a Sinemet 25/100 every four hours day and night. I would not need night doses for PD but RLS shocks and spasms are relentless and literally do not cease unless I take the Sinemet regularly and on time. I'd like to sleep through the night but the leg shocks wake me up practically on the dot of 4 hours. I have tried Klonopin. I have 0.5 mg tabs and took half a tablet at bedtime for a few nights but it made me agitated and anxious and the RLS continued on. Any ideas? how bad was your RLS? Who is JohnCottingham? Barbara yacos <[log in to unmask]>