I asked a former colleague to answer this question and am passing on her
answer. Medical librarians are great!
aloha to all. [log in to unmask] for Paul
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Forwarded message:
From: [log in to unmask] (Heidi's Mac)
To: [log in to unmask]
CC: [log in to unmask]
Date: 95-03-30 16:33:26 EST
Hi,
I was able to pop into medline and determine the generic
for the following-- I included additional info re: broader
terms and the scope notes when available.
Hope you find this useful.
Best wishes
always, Heidi
Naprosyn = naproxen
BROADER HEADINGS: (all have narrower headings)
1.22 Anti-Inflammatory Agents, Non-Steroidal. 4,872
citations
1.23 Gout Suppressants. 12
citations
1.24 Cyclooxygenase Inhibitors. 499
citations
1.25 Naphthaleneacetic Acids. 35
citations
TREE NO.: D4.615.638.472.450 D8.373.310.500 D16.850.15.50.590
D17.25.30.550 D17.50.30.550 D17.50.337.550
PREVIOUS INDEXING: Methyl Ethers (73-74)
Naphthalenes (72-74)
Propionates (72-74)
SCOPE NOTES: 2-(6-Methoxy-2-naphthyl)propionic acid. An anti-inflammatory
agent
with analgesic and antipyretic properties. Both the acid and its sodium
salt are used in the treatment of rheumatoid arthritis and other
rheumatic
or musculoskeletal disorders, dysmenorrhea, and acute gout.
Sinemet/Sinamet (sp?) = carbidopa
BROADER HEADINGS: (all have narrower headings)
1.15 Antiparkinson Agents. 351
citations
1.16 Methyldopa. 155
citations
1.17 Dopamine Neuron Agents (Non MeSH) 0
citations
1.18 Enzyme Inhibitors. 674
citations
1.19 Hydrazines. 552
citations
TREE NO.: D2.92.311.242.538.200 D2.442.200 D8.373.210
D14.100.150.600.142 D15.90.50.150
USED FOR: Methyldopahydrazine.
MK-485.
MK-486.
PREVIOUS INDEXING: Dopa (72-74)
Hydrazines (72-74)
Methyldopa (72-74)
SCOPE NOTES: A peripheral inhibitor of DOPA DECARBOXYLASE. It is given in
parkinsonism along with LEVODOPA to inhibit the conversion of levodopa to
dopamine in the periphery, thereby reducing the peripheral adverse
effects,
increasing the amount of levodopa that reaches the central nervous
system,
and reducing the dose needed. It has no antiparkinson actions when given
alone.
Parlodel = bromocriptine
USED FOR: Bromocryptin.
2-Bromoergocryptine.
PREVIOUS INDEXING: Ergot Alkaloids (66-74)
SCOPE NOTES: A semisynthetic ergot alkaloid that is a dopamine D2 agonist. It
suppresses prolactin secretion and is used to treat amenorrhea,
galactorrhea, and female infertility, and has been proposed for Parkinson
disease.
Eldepryl = selegiline
BROADER HEADINGS: (all have narrower headings)
1.18 Antiparkinson Agents. 351
citations
1.19 Phenethylamines. 548
citations
1.20 Monoamine Oxidase Inhibitors. 866
citations
TREE NO.: D2.92.471.683.915 D8.373.616.900 D15.90.50.800
USED FOR: Deprenalin.
Deprenil.
Deprenyl.
PREVIOUS INDEXING: Monoamine Oxidase Inhibitors (66-78)
Phenethylamines (66-78)
SCOPE NOTES: (R)-N,alpha-Dimethyl-N-2-propynylbenzeneethanamine. A selective,
irreversible inhibitor of Type B monoamine oxidase. It is used in newly
diagnosed patients with Parkinson's disease. It may slow progression of
the
clinical disease and delay the requirement for levodopa therapy. It also
may be given with levodopa upon onset of disability. (From AMA Drug
Evaluations Annual, 1994, p.385) The compound without isomeric
designation
is deprenyl.
Pramipexole = 104632-26-0 (pramipexol)
Permax = Pergolide (Permax, LY127809, CAS 66104-23-2) a dopamine agonist for
the treatment of Parkinson's disease.
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