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I've seen a lot on this list regarding pallidotomies, with results ranging from potentially bad effects, to no effect, to near total relief from symptoms. One thing I haven't heard about, though, is the post pallidotomy prognosis of patients for whom the operation was a success. Maybe that was covered in one of the recent articles, or maybe it's just too soon to tell. I keep hearing the admonition that even though the surgery can potentially relieve symptoms, *it's not a cure*, but just what does that mean? The CNS continues to be low in dopamine, but the cells that were sensitive to the resulting overstimulation are destroyed by the surgery. Are other cells eventually affected by the lack of dopamine? Do the symptoms (or new, different symptoms) eventually come back as the disease progresses? ============================================================== Gary Zimmerman Technical Writer || Internet: [log in to unmask] || _I'm_ an individual too. ==============================================================