My mother was diagnosed with PD a little over one year ago. My father and I have not been able to get her medication straight. She is taking Sinemet and it seems to freeze her up even more. Our Doctor's advice is too just continue "playing around" with the meds until we get it right. We have been "playing" for a year now, with no improvement. We have ruled out any drug interactions. I am curious if anyone has encountered this problem. Thank you!!