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Hi, I have had a new development in my treatment of Parkinson's which I find to be an ever changing process. the latest is that I am taking both Parlodel and Sinemet Cr 50/200. What happens is that about half an hour after taking my medication I become extremely stiff in the shoulder and neck and the tremor in my hands increases. THis can last up to an hour or more and is very uncomfortable. I have made this known to my doctor and we are trying to cut back on the sinemet. I have also been experiencing headache and a coldness in either my hands or feet which may or may not be related. If anyone has experienced any of these symptoms or has any ideas on what to do I would be most grateful for your help. I am 42 have had PD for 4 years and am currently taking 4 SInemet Cr a Day and 45mg of Parlodel. My Email address is: [log in to unmask] Dar Newman