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Dear Claudia, Bradyphrenia refers to cognitive slowing that SOME NOT ALL Parkinson's disease patients experience. It is different from depression (which can also present with cognitive slowing). The way to detect it is by doing certain psychological testing. It probably does not result from the dopamine depletion that underlie the motor symptoms. Currently, there is no definite treatment although in our center we are investigating treatment strategies for this condition. A reference that gives some background is: Bradyphrenia in parkinsonism:a historical view By D Rogers in: Psychol. Med. 1986 May; 16(2):257-65. Yours, Rami Kaminski