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The first time I tried Sinemet 25/100 I got very nauseous. I took one 25/100 tablet after eating breakfast and an hour later got very nauseous. It took 12 hours until I felt normal again. My doctor suggested that I take 1/2 a tablet of 25/100 after breakfast. I would appreciate feedback and any suggestions on handling Sinemet and nausea. Thank you, Bob Garrick, [log in to unmask]