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The logis behind taking 5 mg with breakfast & lunch rather than with the evening meal is to avoid the insomnia some say comes with taking it late in the day. I take Eldepryl and am somewhat confused myself since this MAO-B inhibitor has a very long half life in the body.... The manufacturer is reported to be planning a slow release version with the laser holed system used by Procardia-XL . From what I know as a reader and a user, I see no need for the long life slow release version - except to establish product differentiation to extend patent life. Will Johnston in Salisbuury, MD.