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As a young PD-er, I find that this list is a a fantastic resource. I was very glad to see authoratative information being contributed by Joe Irr of DuPont Pharma. Kudos to Joe for participating! Here's my question about Sinemet CR: Thanks to a previous exchange, I now understand that the formulation of the tablet plays a role in the "CR" aspect so it makes sense not to grind one up. But the tablet I normally take is scored to make it esy to cut in half. Isn't the intent of this to allow one to take a half dose? When I told my neurologist that I would sometimes take a half tablet because it's all I felt I needed, he immediately prescribed the "junior" size for that purpose and admonished me about messing up the the time-release aspect by cutting the tablet in half. What is the proper way to take a "half dose" of Sinemet CR? Craig