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Monica, I was on Permax for a brief interlude, just building up to a therapeutic dose. I hated it- I experienced moments of intense anxiety, like a panic attack. And that was at low dose. When I finally made the connection that these experiences had started at the same time as the Permax, I took myself off of it, and refuse to take it again. Nasty stuff in my opinion. I'd rather have PD symptoms. Kathie Tollifson ([log in to unmask])