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Dear David Boots,
 
     I think that's a lot of Sinemet that your neurologist is prescribing.
 After I got up to about 5 of 25/100, and the dyskenesias began to appear, my
neuro. switched me to permax and we cut way back on the Sinemet.  For awhile
I had terrific dyskenesia, then after awhile I figured out how to regulate
it.  Now I break up the Sinemets into crumbs, and take them when I start to
go off about every 2 1/2  to 3 hours, along with a permax.  Now my daily
dosage of Sinemet is 1 1/2 to 2 a day, 8 to 6 to 10 Permax, 2 Eldepryl , and
2 Amantadine.  I'm 53, and have had PD since age 35, and I"m doing fine.
     If you question your doctor's judgement and can't get satisfaction, just
switch to another.  I've been through at least 6 of them.  Now I finally
trust one.
      Hope this is helpful.              Claudia Elliott