 |
 |
Roger, Received a packet of info via snail mail from Wendy Tebay (Rosa Bosa) this week which included info on hedgehog. It is indeed a promising looking molecule which may generate neurons throughout the central nervous system. It may become an effective way of treating PD, Alzheimer's, and spinal cord injury. I passed the info on to a young friend who's a quadriplegic as a result of an auto accident. Sonic hedgehog, as its called, seems to mediate the differentiation of ventral neuronal cell types in the forebrain, thereby inducing distinct neurons. Smart molecule! Ontogeny, Inc. of Massachusetts is involved in developing recent biological breakthroughs including control molecules that cause differentiation. It is commercializing pharmaceuticals and cell replacement for irreversible (until now!) neurodegenerative diseases. Pat