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Doxepin is a tricyclic antidepressant (trade name: Sinequan or Adapin) which is similar to Elavil, Tofranil, etc. It is an excellent antidepressant with a moderately sedating side-effect (initially). The sleep-inducing properties remain present for 2-3 weeks (and the antidepressant properties often take that long to "kick in"), so, after about this time, it will no longer help one to sleep unless the sleeplessness is due to depression. Its other side-effects are similar to the rest of the tricyclic medicines; and, used for depression, is a good drug. As a "sleeper", its value is usually temporary. Hope this helps. Best, Bob You wrote: > > I have been lurking for about three months and I am very interested in the >infomation here. I have had PK for about six years and I do not believe I am >doing very well. I have developed a tremor in my left arm at XMAS and Am start- >ing one in my left leg now. It has been increasingly difficult to walk as my >off period gets longer and longer. I am being treated with Permax (.50mg 4 time >s per day) Eldepryl (5 mg 2 / day) Sinemet 25/100 ( 2/day ) Sinemet CR 50/200 >(2/day) and amantadine (100 mg 2/day). Because of sleeping problems my Dr. has >perscribed 150 mg of Doxepin per night. > I have just read the 1988 Ed. of Worst Pills Best Pills. It has nothing but b >ad things to say about this drug. I am looking for any feedback. > Thanks > -- ******************************************************** Robert A. Fink, M. D., F.A.C.S. Phone: 510-849-2555 Neurological Surgery FAX: 510-849-2557 2500 Milvia Street Suite 222 Berkeley, California 94704-2636 USA E-Mail: [log in to unmask] CompuServe: 72303,3442 America Online: BobFink "Ex Tristitia Virtus" ********************************************************