I had been intending to post an abstract describing my long history of exposure to toxic materials over the years. This may be of interest. My first notice of what I now know to have been PD's early signs was in 1989 at age 55. Lead: Was avid handloader of sporting ammunition and spent hours hovering over molten lead in the process of casting bullets. Age: 18-21 years Various organic, toxic compounds: Frequent exposure as chemistry major in college, both undergraduate and graduate programs. Some were: benzene, acetone, toluene, xylene. Also inorganic acid vapors, like hydrochloric acid. Age: 19-25 Mercury: Personally worked with pounds of metallic, liquid mercury when employed as a research chemist. Age: 23-25 years Organophosphates (insecticides, e.g. Spectracide): Frequent exposure by inhalation and skin absorption pathways in doing battle with insects in the Southeastern U.S. and in Texas. Age: 25-60 years Chlorinated pesticides: Both DDT and Chlordane frequently used. Age: 25-35 Note: I have been unable to identify any ancestors who were PD-afflicted. FYI. In retrospect - it is a major wonder that I am here at all! Milton McLain