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I also have edema in both ankles and feet, however I believe mine is due to diabetes, or the medication for it. I am taking Glucotrol which according to the PDR can disturb the ADH, (antidiuretic hormone). I stayed off of it for about 10 days and my edema disappeared. I went back on it again and the edema returned. I know that is only anecdotal evidence, and not proof but MY tentative conclusion is that the oral medication causes edema. ---Milo Milo V. Anderson Box 417 Angwin, CA 94508 VOICE 707 965-2508 EMAIL [log in to unmask] On Sat, 22 Jul 1995, Irving Morgenroth wrote: > I am 62 and have been diagnosed with PD for about 3 years. In addition > to the usual bradykinesia which makes walking difficult, I tend to > swell, from time to time, at my ankle or over my instep or, as is the > case at present, at the instep and toe. It usually is only one foot at > a time (thankfully) but it can be quite an impediment to walking. My > neurologist is not sure that is connected to my PD. > > I have had numerous tests and the only suspicious result is the > presence of protein in the urine, a condition I have had in very small > quantities for some time - and remaining stable. A nephrologist > suggests there may be some kidney problem, but tests indicate quite > adequate kidney function and no adverse change in the last five years. > > Obvously, the edema became apparent as my PD progressed. Anyone having > similar problems? >