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Dear David, I stood in my bathroom in December 1991 with urine running down my leg be cause I could not get my zipper down or even undo my belt. I went to India in January of 1992 & 1993 to have long term Ayurvedic and yoga therapy. When I came back most of my symptoms other than tremors, rigidity, and weakeness had dramtically improved. My memory came back, my uncontrollable urges to urinate disappeared, I could go all night without getting up to urinate, my digestion & eliminations improved, all of the stiffness went out of my joints, but rigidity remained in my muscles. All of this hap- pened before I began taking Sinemet in September of 1993. Since then I have taken Chinese herbs, homeopathic remedies, psychotherapy, feldenkrais, massage therapy, crainiosacral therapy, somato emotional release, acupunc- ture, and recently body alignment technique and Chi Gong treatments. The point I am trying to make is that you are not a victim. You helped create this desease with you mind, emotions, and attitudes. All of the therapies I have taken have each pealed away a layer of onionskin which has allowed me to bring healing into another area of my life. Sinemet, Deprenyl, pallidotomies, etc. are all useful in dealing with the symptoms of PD. The actual causes lie within you and only you hvae the power to eliminate them. This is a slowly emerging model of disease, this responsibility for our own health and well being. We certainly have an unconscious role in creating our diseases otherwise why do only certain people get certain diseases even though many are exposed to the same envirnmental and social factors. Use the meds but look within yourself for the key to healing. I have also done tissue cleansing using herbs and special diets and supple ments, but mental & wemotional cleansing is required too. If you want your substantia nigra back, first eliminate what is destroying it. Look for your own answers. Could it be your fear of expressing anger? Your control over your emotions and your life? Are you afraid to express yourself in the world? Everyon ehas their own story. Read the stories of people who have healed themselves of every concievable disease. They all have one thing in common, they radically transformed their lives and often went through what can only be termed a spiritual transformation. They found a purpose for living and often realized why they had developed a disease in their life. It is a learning experience, check it out. Hang out with prople who are healing their lives, transforming themselves into a higher level of being As long as you think you are a victim, you are one. Take control of your life and look for your own answers and healing. Healing does not come from drugs or surgery, it begins and ends with you. Don't be afraid to ask in your own way for help from a higher power, millions of alcoholics can't be wrong. If you want to talk send me a note. Read for awhile before you make your first move. You may not be able to become completely healed on a physical level, but from my own experience, you can certainlt stop any further degeneration and reverse many of your symptoms. The motor neurons are very difficult to regenerate, but I believe it can be done. I'm still looking for answers, but if you don't look you will never find any.