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Roberta, early on in my p.d. I did experience some weight loss, but its been quite a while since that episode and I have since changed meds. Unfortunately it has been my experience to GAIN from these new meds (but they ar doing the job well) so I have to trade off some-thing. Since he is not taking any meds, I suggest that he question his doc abt that....(question) if I has p.d. as u say, why is he not on a strict med program for it....what ar his symtoms?? joyce