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CRADAs (cooperative research and development agreements) Today my librarian showed me this great article from-- SCIENCE NEWS Vol . 148 July 29,1995 Page 73 Somatix & LBNL estab. a $3.5 Million, 3yr CRADA LAST mAY TO TEST A possible treatment for PD. bEFORE GETTING INVOLVED IN THE crada, sOMATIX RESEARCHERS HAD induced PD in 25 rhesus monkeys. They then inserted into the primates' brains genetically engineered cells that overproduce an enzyme which promotes the production of dopamine, explains Edward Lanphier of Somatix. The new cells should boost patients' production of the neurotransmitter. Last year, after the monkeys got their new cells, LBNL scientists monitored the animals' dopamine production with both positron emission tomography (PET) and singlephoton computed tomography scanning devices. The treatment looked so promising that the company hopes to start human trials next year.