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Drug interaction (reaction?) Caution to all of you in PD cyberspace. I have just returned from the emergency room after taking a beta blocker: ATENOLOL 50 mg tablet. No information exists regarding possible interaction with antiParkinson drugs and after thorough checking the dr. assumed it would be safe for me to used to attempt to correct heart arrhythmia (skipping about 100 beats per hour). What happened? Thurs p.m. 50 mg atenolol - no reaction Friday p.m. second dose - 50 mg atenolol. Approximately 30 minutes after taking the second dose I experienced tightening in throat, left side of face, then tremor, then severe dyskinesia and dystonia developing within 10 minutes of onset of first tightening of muscles. Called dr. and husband (should have called 911) and was in ER within 20 minutes flailing arms and legs to kingdom come. Intramuscular injection of Benadryl slows this movement down within 5 minutes or so. (Benadryl would not slow PD caused dyskinesia according to dr.) Use caution when starting a newly prescribed drug. . .even if the checks are all made by the pharmacy, etc. Good luck to all of you Rita Weeks (My PD drug regimen is: Sinamet CR, Eldepryl, Cabergoline, Premarin (post husterectomy in 1983). Age 50. Multiple drug allergies.........but beware and be careful.