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HI, Joan Wollen <[log in to unmask]> I recently have added Permax to Sinemet CR (25/100) and Eldepryl. Wow did I get a reaction. Hypostatic Hypertension- is that it? Caused me to get very light headed and drowsy-almost couldn't make it to the bathroom at night, had to get my wife to help me. Still have only been able to take 4 x (.o5) pills a day, but it is gradually getting better. Tomorrow I will try for .25 ( a long way from the goal of 2 or 3 mg.) Did Percy have problems like that when he first started Permax? If I took much more Permax, I think I would be more than just confused. I am curious to know why a dopamine agonist was added at the time of surgery. Was it unrelated to the surgery? I am trying to learn more about this drug - its benefits and downside. ----- I didn't realize I would get to be such a chatterbox on this net. As I think about it, as a retired teacher who talked much of the time it should have been expected. Probably not only still in denial in addition to needing to get tons off my chest/rather out of my head. Probably never will be satisfied with what I know. Hope everyone will understand, still have many questions. Who else can I talk too? While I've got your ear/ or rather eye/ have you too doubted the competence of your doctor? As I read these digests and the archives I get the unmistakable feeling that PD, its diagnosis and attempts to "cure"/read lessen the progression and pain/ is not only very complex but also incompletely understood by most of the profession. That's not quite what I meant. Nuts! Let's say I'm not so confident my doctor really know what he is doing even though we get along fine. Why am I so negative? Was it John that sent that informative stuff on Incontinence? Can you understand that? It's far more than my urologist wanted to tell me. Not because of the jargon I suppose. For years I have had a bladder problem and "partial" impotence. The prostate (I'm 68) is somewhat enlarged and probably contributes to my problems, but I think the PD has had its influence for quite a while without my knowing about it. Now I am in the process of sorting all this out with my urologist/ university head of Dept. and research oriented. Thanks very much for the articles. O.K. I will shut up now and get back to bed and try to sleep. Fred