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The types of vitamin and mineral supplements and their dosages are recomended in the book Presecription for Nutritional Healing Balch and Balch Avery Publishing Group Garden City Park, NY To quote the section on Parkinson's Disease: "Parkinson's disease is a degenerative disease affecting the nervous system. Its cause is unknown, but symptoms occur when there is an imbalance of dopamine and acetylcholine in the brain. Scientists found a deficiency of dopamine in certain brain cells. This chemical carries messages from one nerve cell to another. When the brain is not able to manufacture dopamine, Parkinson's disease results. Malnutrition is believed to be a major underlying factor. The drug most often used treat this disease is levodopa;however, it isn't effective alone and can have serious side effects, including paranoia and hallucinations. If taking this drug, do not take B6. Taken together, vitamine B6 and levodopa elevate brain dopamine. Using B6 alone is probably safer and is as effective." Since we have done nothing besides craniosacral therapy for her symptoms, we thought it prudent to try supplements first. This summer has been very hard on both of us. Our therapist moved away and she went without cranio- sacral therapy for two months. She couldn't raise herself out of a chair or get into bed without assistance, couldn't walk without falling unless firmly assisted. Monday after two weeks of the megadose supplements she got up without thinking and walked through the house. She is still a little unsteady on the curves and in turning around to sit down but what an improvement. Begining this week she is taking 1 cc of B6 by injection once a week. I don't know anything about within or outside the blood brain barrior. I only know what I see. I'm very hopeful this is all cause and effect and that she continues to improve or at least stays as good as she is not. Carol Brow [log in to unmask]