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Dear Joanne, You're almost right, except for two things: The surface of two half pills is not the same and the structure of place where the pill is broken is different. Specially the structure changes can speed up the melting of the pill and reduce the time the pills are working. On the contrary the bigger surface can increase the time. I myself have tried several weeks breaking my pills in two parts, but I don't notice any difference with a subscribed use of the pills. If you mix your pills with water for a whole day in advance, you have to add vitamin C to your liquid sinemet so it won't oxydate. Kees Paap Be serious, have fun! >I can't believe that the Sinemet CR has the timed release in one half of the >tablet and the Sinemet in the other. No medicine that I know of has those >characteristics. Half a tablet or capsule is half the medication, whatever >it is (half an aspirin, half a tetracycline pill, half a birth-control pill, >etc.). I'd challenge the doctor on this--and maybe get another doctor. > >Joanne Sandstrom >[log in to unmask] > >