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Alan Bonander wrote: > > Carol Brow: > > I couldn't help seeing that your mother was taking 1000 mg of B6. According > to the PD books, B6 converts Levodopa to dopamine outside of the blood brain > barrier. One thing that Carbidopa does is to lower the B6 level such that it > is less ffective in converting Levodopa outside the BBB. Ok, let me understand this. If you are taking Levodopa, you can lower your dose by avioding B6 or taking Carbidopa to inhibit effects of B6. > > It is interesting that having a deficiency of B6 will show symptoms similar > to PD. In some ancedotal trails, it was found that PD patients on long term > Sinemet or Carbidopa/Levodopa (maybe 10 years or more) may find increased > benefits from the same amount of Sinemet by taking about 50 mg of B6 nightly. Ok, let me understand. If a normal person has a low B6 level, the body can't make dopamine inside or outside of the brain barrier, hence PD symptoms. Correct? > > > This is a far cry from your 1000 mg. I would suggest you read up on B6 and > see if you want to keep it at this level. > > Regrads, > Alan Bonander ([log in to unmask]) > So it sounds like should take B6 until you go on Levodopa. But if extra dopamine is toxic (Levodopa speeds the rate that damage occurs apparently) then people should avoid B6 even before going on Levodopa. Comments on this idea from Alan or others? Jason Taylor __________________________________________________________________________ Jason Taylor | "Doctor, don't cut so deep! Greenbelt, MD| That's the third operating table you've ruined this week!"