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JOE, While your at it can you tell us why Dupont hasn't come out with smaller dose tablets of regular Sinemet. Many of us are extremely sensitive to small changes in dose and need to take small doses frequently. Even with Entacapone which I have been taking as part of a study and has worked better for me than the CR I still take 25-100 tabs 8 times a day breaking pills into small uneven pieces with doses as follows, 1 1/4, 1, 1/2, 3/4, 1/2, 1/2, 3/4, 3/4. It is quite inconvenient and inaccurate. What does Dupont have to say about that possibility. Charlie >Bill Berman gave some pretty good advice about being careful when breaking >the large Sinemet CR tablet, the 50/200 one. Be careful and it will work >pretty well. There should be another note from me on the breaking of Sinemet >CR. > >Best regards, >Joe Irr > > **************************************************************************** ************************************* Charles T. Meyer Madison, WI [log in to unmask] **************************************************************************** ************************************