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To Charlie Meyer, Hi, I'm new and a caregiver at the moment for my mother. My dad must break her Sinement CR in half for sensitivity reasons. I asked our pharmacist about getting even dosage, even by utilizing a pill breaker, and was assured all should be well. She did add in my query as to why they were not given in lower doses....that Dupont would not charge you half-price! Oh so true...especially for some of my own antidepressants, etc. BTW, men with depression having erection troubles might want to check into Serzone (nefazadone). Due to pressure from the male population, this drug seems to alleviate the impotentcy problems associated with the designers like Prozac, Zoloft and Paxil. Of course, you need to check with your doc for contraindications. Have some initial info that it will not interfere, but best to check naturally. As a woman, I swear by it now. It has given me back my marriage! Further on pill division. My father had to take Demerol after an ankle fusion. They only make 50's in tablets and 25's in injectibles. Silly, isn't it. He is 80 and only needed 25. It's a pain trying to cut a pill that is about 1/16th inch in diameter. Guess they want you to get off on the painkiller without regards to your safety! Again, it would cost as much for the half tab dose said my pharmacist. Bulk seems to be better...only in America folks. Am glad to be here. Will be "listening" mostly, but want to know I feel so well informed after having subscribed....thanks so much to a very special person who set me up on here. Thanks Alan B. Regards, Lauren Wright Brown