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Lisa and Jeff, This may not relate to your circumstance, but early on in my treatment while I was taking amantadine (symmetrel) I experienced typical symptoms of Raynaud's phenomenon in which my fingers and toes became blue then white during cold weather, and warm gloves and shoes had no appreciable effect on the resultant discomfort. Subsequently I went off amantadine and the symptoms disappeared never to return. Hope you find the solution to your problem. Gaylord Rough ([log in to unmask]) z