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I TOOK ARTANE FOR ABOUT 10 YEARS. i MOVED TO ANOTHER CITY AND MY NEW DOCTOR DID NOT WANT ME TO TAKE ARTANE. SO HE TOOK ME OFF OF IT ALL AT ONCE. I ALMOST IMMEDIATELY STARTED REGRESSING. I WAS ALSO TAKING SINEMETCR/ELDEPRYL AND PERMAX. i WENT BACK TO MY ORIGINAL DOCTOR AND HE STARTED ME ON AMANTADINE AND NORTRIPTYLINE. i STARTED IMPROVING IN A FEW DAYS. i HAVE SINCE T HAT TIME HAD TO DOUBLE MY MEDICATIONS. SO I AM WONDERING IF STOPPING THE ARTANE WAS A FACTOR IN MY REGRESSION OR WAS IT JUST THE PROGRESSION OF MY DISEASE. i AM SURE I WILL NEVER KNOW FOR SURE. THE POINT THAT I AM MAKING IS THAT WE HAVE TO CAREFULLY BALANCE OUR MEDICATIONS AND I AM VERY GLAD THAT I AM NOW SEEING A VERY COMPETENT NEUROLOGIST. HOW ARE ALL YOU PERMAX PATIENTS DOING. Carol Gray <carol.gray@ ail.industry.net>