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Jane Frederickson of MI, has the following questions: I've had PD for 17 years and experience levodopa fluctuations and am protein sensitive. Is there anyone with similar situations, or found anything to augment or enhance levodopa. I'd like to be mobile from 7 AM to 7 PM. Also, is anyone using, or has used Permax. If so, have you felt worse during off times--for example-more difficult walking, experience general weakness especially in legs-stiffness/rubbery sensation. How long was Permax effective when on it? Thank you Replys may be sent to the list or to [log in to unmask]