Here's another, tying in environmental exposures, with personality and other possible predetermining factors: I don't think ya'll can tell from the messages about these abstracts which I'm sending here, but I'm also sending copies to congress/senate personnel, and also to ABCNews, as they've had some recent episodes on Prime Time Live and/or 20/20 on the subjects of PD & pallidotomies, as well as separate ones on the health effects of Dioxin and of your average everyday, 'household' pesticides. Perhaps I can generate enough interest in further attention to combo of these issues. By the way:; Ruth - I personally don't know why fertilizers too were studied other than to get an idea about the effects from all chemicals routinely used by farmers. Dr. Norm Archer - That's all the info I've got at the moment as to the details of these studies. I may eventually try to get full copies of the articles, which would hopefully have more info. As to alternatives to these chemicals, there are many, and I think as Ruth noted, info on them is readily available, but in order to really have the alternatives incorpoarated into routine pest management, we need both a change in attitude and the also difficult change in the entrenched chemical/pesticide industry. I guess the only way that'll happen, especially in a political cliimate where the environment is once again going to get a very short-sighted shaft with much of the pending legislation, is when People, vs mere animals, are proven to also be victims. We have voices, and they don't, so once enough of us get ill & fed up, maybe they'll listen. In the meantime, I trying to stir the pot, and I'm also looking in to volunteering for a local wildlife preserve which also promotes sustainable use of resources and organic agriculture. I can't just complain about these issues, I want to be part of their soluton, regardless of the final verdict with respect to pd. (That was my little spiel for our hidden audience!). Anyway, here goes: ************************ 2 AU - BELL IR AU - SCHWARTZ GE AU - AMEND D AU - PETERSON JM AU - KASZNIAK AW AU - MILLER CS TI - Psychological characteristics and subjective intolerance for xenobiotic agents of normal young adults with trait shyness and defensiveness: A Parkinsonian-like personality type? SI - BIOSIS/94/26225 SO - JOURNAL OF NERVOUS AND MENTAL DISEASE; 182 (7). 1994. 367-374. AB - BIOSIS COPYRIGHT: BIOL ABS. The present study examines the psychological characteristics and self-reported responses to xenobiotic agents such as tobacco smoke and pesticide of normal young adults with personality traits similar to those claimed for Parkinsonian patients. Previous research, though controversial, has suggested that persons with idiopathic Parkinson's disease (PD) have premorbid personality traits that may include shyness and repressive defensiveness. Other epidemiological evidence indicates that PD patients may have premorbidly increased prevalence of anxiety, affective, and/or somatoform disorders; decreased rates of smoking and alcohol consumption; and elevated exposure to herbicides or pesticides. A total of 783 college students enrolled in an introductory psychology course completed the Cheek-Buss Scale (shyness), the Marlowe-Crowne Social Desirability Scale (defensiveness), Symptom Checklist 90 (revised), the Mastery Scale, a health history checklist, and rating scales for frequency of illness front alcohol and 10 common environmental chemicals. Subjects were divided into four groups on the basis of above versus below-median scores on the Cheek-Buss and Marlowe-Crowne scales (persons high in shyness and defensiveness, those high only in shyness, those high only in defensiveness, and those low in both shyness and defensiveness). The group high in shyness but low in defensiveness had the highest, whereas the group low in shyness but high in defensiveness had the lowest, total scores on the SCL-90-R; the two shyest groups were lowest in sense of mastery. Similar to PD, the group high in both shyness and defensiveness overall reported the least number of smokers (10% vs. 19% in those high only in shyness, 17% in those high only in defensiveness, and 28% in those low in both traits, p < .001); differences within women largely accounted for this finding. Subjects higher in shyness and/or defensiveness rated themselves higher in frequency of illness from a small amount of alcohol than did those who were low in both shyness and defensiveness. The group who was high in both shyness and defensiveness tended to report the highest frequency of illness from pesticide as well as other xenobiotic odors (e.g., newsprint). Taken together with previous research, the findings suggest that certain young adults high in shyness, and especially those also high in defensiveness, may be among the subset of the population at increased risk for PD later in life. MH - HUMAN MH - SOCIAL BEHAVIOR MH - ECOLOGY MH - BEHAVIOR MH - HUMAN MH - BIOCHEMISTRY MH - NERVOUS SYSTEM DISEASES/PATHOLOGY MH - MENTAL DISORDERS/THERAPY/PATHOLOGY MH - PSYCHOPATHOLOGY MH - MENTAL DISORDERS/PHYSIOPATHOLOGY MH - PSYCHOPHYSIOLOGY MH - *POISONING MH - ANIMALS, LABORATORY MH - ENVIRONMENTAL POLLUTANTS/POISONING MH - OCCUPATIONAL DISEASES MH - HERBICIDES MH - PEST CONTROL/METHODS MH - PESTICIDES MH - HOMINIDAE RN - 28289-54-5; 110-54-3; 64-17-5