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My name is Lloyd Stewart, I am 52, almost retired medical practitioner, and have had PD for 8 years. I try and write, and have some case studies hopefully being published. I have three daughters who live away from home. I am engaged to Janine, who is able to see me at weekends, and who is the joy of my life, since she met me when I was not well. The things I like to do include gliding, homebuilt airplanes, eye operations, community health, research, teaching, writing. I have worked in Aboriginal health, psychiatry, nursing education (human bioscience) general practice, leprosy, and was an eye sugeon when I got PD. I amuse myself trying to solve medical problems which are rare, or to educate people about their illness, doing literature searches etc. I take selegeline 2.5 mg per week, acetazolamide 65 mg/day, and 200 mg/day sinemet CR. Even on this low dose, my mood swings up and I get euphoric. If this upward swing continues it eventually leads to delerium, so I take 100 mgm sinemet CR so my mood slows down and I can barely get dressed. If 100 mgm doesn't help small doses of valium, and/or no sinemet for 2 or 3 days restores me to normal mentally. I am trying 250 microgram of clonazepam daily since higher doses made me into a zero blood alcohol drunk driver and made me sleepy and very slow. I can find no references to trials of treatment such as mood stabilisers for moodswings, bipolar, hypomania or mania in PD. If anyone can help I will be eternally grateful. Box 608 Wangaratta 3676 Australia +57 221627 [log in to unmask]