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My father is an 85-year-old Parkinsonian, with very unclear speech. My mother, who is his primary caregiver and who, together with the neurologist, tries to keep medications well adjusted, writes as follows: "I was interested in the letter in the Parky List from the person who had cut down and then cut out the Permax. For the past two weeks I have been cutting down on daddy's Permax and now he is getting just half of what he had been having: 1 1/2 grams a day instead of the 3 grams. I think it helps his speech somewhat, but I can't be sure. If you are "talking" with the list people you might inqure if anyone has experienced better speech after cutting down on Permax. Otherwise it seems to make no difference." Has anyone else had such experience with Permax? Robert Bley-Vroman http://www2.hawaii.edu/~vroman