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-- [ From: Donna Kipp * EMC.Ver #2.10P ] -- Re: Jane Frederickson question on Permax. I find that Permax works quite effectively for me for some time then I start becoming very stiff and overdosed I then have to switch back to parlodel. I have to do this every 9 mnthe or so. My theory is that the Permax builds up in my system and I need a rest period from it . I sometimes use Benedryl to supplement my meds. Donna 48.9