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Dear Sonia: You wanted to know about my pre-pallidotomy symptoms. Everything on the menu except bad tremor would describe it succintly. My "therapeutic window" had effectively slammed shut. Without Sinemet, I could hardly move, even sitting in a chair was hell - about all I could manage was lying flat on my back. I was really good at that. With Sinemet, during my 45 minute long "ON" periods, I was flailing like, well, a flail. Bad diskynesias, arms , legs etc. It's kind of hard to believe, in retrospect, what my family had to put up with. They were terrific the entire time, even though I would become somewhat cranky, on occasion. I sincerely hope this information has been of some use. Best of luck with your decision. William Berman