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On Mon, 18 Sep 1995 17:35:50 Ron Herstell wrote: < The thing I find most puzzling is that I feel wonderful in the < morning when I first get up out of bed - at a time when I have been < without medication for about nine hours - then it's downhill all the < way! My neurologiast says that this sometimes happens and is OK. < I know of only one other PD person like this and just wonder if there < are any more like that on this list? Ron, I often experience the same phenomena. I also ride an exercise bike for 45 minutes most mornings before I take my first dose of medication and this improves my condition even more. Except for mild bradykinesia you really couldn't tell I had PD. This condition lasts for about a couple of hours and then I become a total basket case if I haven't taken my meds. I just turned 54 and was diagnosed with PD 7 years ago. My regimen is: Sinemet 25/250 1 tab tid Eldepryl 5 Mg 1 tab bid Pramipexole 1.5 Mg 1 tab tid (Phase II trial medication) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Bruce G. Warr "Experience is what enables us to recognize Healthcare Informatics Lab a mistake the next time we make it." Information Systems Dept. University of Maryland Baltimore County http://umbc.edu/~warr/ (V) (410)455-3206 (F) (410)455-1073 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~