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While I have benefited greatly from my meds, they have caused plenty of grief also Some psychactives have been dangerous My friends at the Syracuse VA did a super job with Cogentin--for my spams--A new man as they say BUT Serenity is very powerful also. Without serenity the body and mind will split in the wrong way, with emotions/fears etc spreading into other parts of the CNS and perhaps loss of real muscle capability also. Meds do not build neuron connections; visiualization does -- to the best of my knowlede based on a MRI back in 1985. I have dove so deep that I seemed to be looking at my Sub.nigra --who really knowsif i really saw it. The odds are PD will not kill you. Lack of friends will. I saw it at the VA Home. I do not like some of the negative thoughts especially you YOPDers--venting is great but cold blooding biyching is not. You have many years Use them. Edmond