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I have neck problems also. Tortacollis. I have a Botox injection every three months of 250 units. I was at 300 units but experienced some of the problems your mother exhibits. It sounds to me like she was given too much Botulinum. I recently went off Artane because of it's side effects on cognitive functions. However, Artane helps deal with the Tortacollis and so again we have a good news bad news story in PD meds. The big problem with the Botox injection, beside the high cost (mine cost $1400 per shot), is that you will develop anti-bodies rendering the treatment ineffective. The effectiveness of the Botox treatment is clearly dependent on the Dr. giving the shot. My first neurologist did random injections in the neck muscles. The first time worked great. The second time nothing. I now have a neurologist doing the injections who uses sensing equipment with needles to determine what muscles are rigid and need treatment. Much more effective method. I get a shot every 3 months but usually the last month is difficult. I use a massage therapist who works on my neck once a week and she helps extend the time between shots. I also went through biofeedback therapy for the tortacollis. It proved effective in relaxed conditions but when I was under stress I could not overcome the muscles with this method. Hope this helps David Rohrbaugh [log in to unmask]