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I am inquiring as to what can be done related to stiffnes and limited movement just after taking medicaiton. I am finding that for about 45 minutes to an hour after taking my medication that my neck shoulders and arms become more stiff and it is difficult to move. I am on Sinemet 25/100 (2 tabs 5 times a day). Eldepryl once a day and permax (.25 3 times a day) I went from the Sinemet CR back to the regular sinemet due to the time released building up in my system. Now I am trying to regulate the stiffness that happens just after taking my meds. This can last up to an hour and is very annoying when in the middle of things and you have to stop to let things even out. This problem also increases by 10 times during my cycle and any help that you can offer would be appreciated by myself and my neurologist as we are at a loss. Dar Newman [log in to unmask]