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There is a 25/100 CR in addition to the regular one of that dosage-- we have a bottle of them--they are the same color as the 50/200 six ze but much smaller. Ask your doctor about them! It is confusing to have the same dose available in both forms, so be sure to specify Sinemet CR when you ask about it. Camilla and Peter(who takes it sometimes)Oxford,OH PS Chuck--will add you.