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In a message dated 95-12-02 22:13:39 EST, you write: > However, pointing a finger at the > use of modern fertilisers and pesticides doesn't explain the existence > of the disease in earlier generations It's not necessarily a lock and key kind of response to stimuli. If a hereditary increase in susceptibility to agents which cause PD exists, a variety of causative agents (old and new) might fit the bill. Delana Vaughan