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Gabrial, EPS (extrapyramidal syndrome) is a family of movement disorders that can be related to, or unrelated to PD. They are characterized by involuntary movement of the face, lips tongue, neck, trunk, legs, feet, even the intestinal tract and throat. Ther are so many expressions of this disturbing class of symptoms that a detailed discription of each one would not be real helpful. They are due to complex disturbances in neuronal tracts extending from the midbrain down to the spinal chord. They can be associated with the administration of any of several medications including neuroleptics (haldol, prolixin, clozaril (this one reports a reduced level of EPS)), tricyclic antidepressants (elavil, tofranil, etc.), among other agents. Many refer to EPS as side effects of these meds; I prefer to consider them to be major activities of these medications that are without medical benefit. Jeffrey M. Tosk, Ph.D. Director, Parkinson's Research Center La Sierra University [log in to unmask]