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I think if my neuro suggested a new drug, but warned me that the following side effects would result from its use, I would immediately throw it in the trash! The issue of the quality of this person's life is paramount, compared to concerns about possible side effects from PD drugs. Depression and anxiety have taken control, and it sounds like the physical impairment is extensive enough to warrant giving up driving unless treated symptomatically. The thought of surrendering my license does not top my list of favorite thoughts! I wouldn't be surprised to find out that some of the symptoms presently being treated as a heart condition, might be the result of anxiety, and could disappear almost overnight with proper meds. I frankly can see no justification for postponing the use of PD meds. I think there is a MUCH brighter day ahead for this poor gal. Happy Holidays to you all! I am enjoying every minute of this season, especially with the temporary reprieve of my nose from the grindstone! Kathie Tollifson >Cannot write, type, play piano: anything precise. >Severe back, neck, and shoulder muscle stiffness and pain >Increased walking gait problems-look like a clown >Headaches >Nausea from pain and depression >Intense weight loss over last 2 months due to inability to eat from nausea-15 >pounds and falling. >Toes and foot cramping and freezing, making walk difficult. >Major depression and anxiety, not helped, so far, from array of trial >anti-depressants. Inability to concentrate and short-term memory loss >Extreme fatigue-feel like legs are falling out from me. >Difficulty switching from car brake to accelerator due to decreased foot >movement >(Need for handicapped parking permit) >Lack of control of emotions (spontaneous crying) Lack of patience >Inability to button buttons and zip zippers >Occassional migraines from muscle stiffness >Had to go on leave of absence from Crisis Center because can't sit, answer >phones, and take notes without onset of almost all symptoms >Inability to sit for any periods of time due to muscle pain and stiffness >Inability to "work out physically" due to pain, stiffening, and fatigue >Frequent urination >Heart problems have worsened possibly due to stress, resulting in two >emergency hospital visits, one by ambulance. On new heart medication in >ddition to Toprol >Occasional loss of balance >Terrible insomnia >Frustration >Inability to find physical comfort in any type of reclined position >Slurring of speech, pointed out by several people >Lower audibility of speech, as represented by people constantly asking me to >speak up; that they can't hear me >Extreme difficulty bending down to get into car or pick up things off >floor-decreased mobility >Constant strains to back etc., due to minor incidents, triggered by stiffness >Back, neck, and shoulder spasms >Inability to remember procedures in sequence, such as CPR >Difficulty in making decisions >Extreme difficulty signing name on anything: checks, charge slips etc. >Extreme difficulty trying to walk up hills of any ascent >Dragging of right leg when walking > >