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I dont want to remember before I started the Liquid Sinemet routine 8 weeks ago, but in the last 8 weeks I can say that my added activity has no effect on my dosage. There have been weekend days that Chuck and I am up and out of the house at 10AM walking NYC and having dinner with friends and returned at 11PM tired but supremely satisfied that I made it through the day. What makes you feel that your activities use up your sinemet. BTW try 1200mg delay release B12. Happy holiday joyce