Have long been communicating with this person....need some (more) help from all of you (have already received soo much for me and my husband....Thank You!!) . Please excuse me for being so 'mysterious', at this point this person does not feel able to communicate directly with 'us' (most, if not all of you will understand). She is not currently on any meds (although positive DX for PD 2+ yrs ago..is reluctant to do so , although I have tired to encourage), is trying to find the way...has sent me the following (as she will be seeing the Neuro on the 26th for futher evaluation)...Would those of you wonderful people 'out there' who are willing provide some input (for me to foreward to her to try to help out?)...which of these symptoms did you have...did Sinamet (or other drug) help/stop any of the following? When (right away, or did you hold off for awhile) If you chose to start taking it/if not why not??..(My husband started right away and has been helped)..she is very frightened of the possible 'side/wearing off effects')......Thank You in advance for helping me help her!!!!!!! (Part of the reason we are all here I think) Bless you all, I'm so glad I "found" you. ..... Roberta PS:There may be other problems in this case also...but I would very much appreciate any response any of you will give me...I am sorry if this post is too long!!!!!! Following is from her....symptoms, etc.... will foreward any info to her ASAP!!!! This list is for my upcoming doc appt. Anything I've missed out that I've told you about Cannot write, type, play piano: anything precise. Severe back, neck, and shoulder muscle stiffness and pain Increased walking gait problems-look like a clown Headaches Nausea from pain and depression Intense weight loss over last 2 months due to inability to eat from nausea-15 pounds and falling. Toes and foot cramping and freezing, making walk difficult. Major depression and anxiety, not helped, so far, from array of trial anti-depressants. Inability to concentrate and short-term memory loss Extreme fatigue-feel like legs are falling out from me. Difficulty switching from car brake to accelerator due to decreased foot movement (Need for handicapped parking permit) Lack of control of emotions (spontaneous crying) Lack of patience Inability to button buttons and zip zippers Occassional migraines from muscle stiffness Had to go on leave of absence from Crisis Center because can't sit, answer phones, and take notes without onset of almost all symptoms Inability to sit for any periods of time due to muscle pain and stiffness Inability to "work out physically" due to pain, stiffening, and fatigue Frequent urination Heart problems have worsened possibly due to stress, resulting in two emergency hospital visits, one by ambulance. On new heart medication in ddition to Toprol Occasional loss of balance Terrible insomnia Frustration Inability to find physical comfort in any type of reclined position Slurring of speech, pointed out by several people Lower audibility of speech, as represented by people constantly asking me to speak up; that they can't hear me Extreme difficulty bending down to get into car or pick up things off floor-decreased mobility Constant strains to back etc., due to minor incidents, triggered by stiffness Back, neck, and shoulder spasms Inability to remember procedures in sequence, such as CPR Difficulty in making decisions Extreme difficulty signing name on anything: checks, charge slips etc. Extreme difficulty trying to walk up hills of any ascent Dragging of right leg when walking